A sort of a remake of the Anaconda movie of 1997 with Ice Cube and Jennifer Lopez with cameo roles. Four childhood friends decide to rekindle their passions of youth, and make an Anaconda movie. Ronald (Paul Rudd) recruits his friends to travel to the Amazon to make a movie, telling them he has the right to Anaconda, their favorite movie as youth. He recruits his best friend, Doug (Jack Black) and old crush, Claire (Thandiwe Newton) and Kenny (Steve Zahn) to run the camera and technical stuff. They are on their way to Brazil where they meet snake handler, Santiago (Selton Mello) who is obsessed with his snake. However Ana Almeida (Daniela Melchior) high jacks their boat, with them on it and recording their movie on the way.
There is a really creepy scene with the snake. Santiago holds it in Ronald's face, an he reacts, and kills the snake. Santiago leaves the boat to find a new snake; the new snake gets him instead however. Now the snake has a taste for people and is after them. Worse yet, Ana is a smuggler of gold. Of course the snake gets her. And in truth Ronald does not own the rights to Anaconda, as those who do, show up making their own movie. But that doesn't last long as the anaconda destroys their set and is after them as well. It doesn't discriminate. Amidst the chaos our four are trying to get away, but Doug gets devoured by the snake, and somehow spit up hole. He appears dead. They rap him in a pig so as to create a diversion and they can get away. They put a squirrel in his mouth. However he is not dead and the snake is boring down on him. He runs, eventually the snake gets the pig and not him.
This movie has some funny parts. The characters run away a lot and seem to run in a funny manner. The four rekindle their relationship and form a stronger bond. And Doug gets to make the wedding video for Claire and Ronald.
